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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
DSN1
All Species:
12.12
Human Site:
T250
Identified Species:
38.1
UniProt:
Q9H410
Number Species:
7
Phosphosite Substitution
Charge Score:
-0.43
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9H410
NP_001138787.1
356
40067
T250
G
S
T
E
A
K
I
T
E
V
K
V
E
P
M
Chimpanzee
Pan troglodytes
XP_514622
399
44351
T293
G
S
T
E
A
K
I
T
E
V
K
V
E
P
M
Rhesus Macaque
Macaca mulatta
XP_001094009
354
40066
T250
G
S
A
E
A
K
I
T
E
V
K
V
E
P
M
Dog
Lupus familis
XP_852834
354
40008
T250
T
S
A
E
T
K
V
T
E
V
E
V
E
P
K
Cat
Felis silvestris
Mouse
Mus musculus
Q9CYC5
348
39534
R248
P
R
G
S
T
E
T
R
I
T
E
V
K
V
D
Rat
Rattus norvegicus
NP_001020939
348
39677
K248
P
R
G
S
T
E
T
K
I
N
E
V
N
V
D
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
NP_001038125
349
38599
R249
S
R
Q
L
E
E
C
R
S
K
E
G
R
A
E
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
XP_001923648
330
36657
G230
L
N
K
C
V
E
R
G
E
D
T
G
V
P
L
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
65.6
94.3
79.4
N.A.
70.2
69.9
N.A.
N.A.
38.7
N.A.
24.1
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
100
71.4
96.6
86.5
N.A.
79.2
78.9
N.A.
N.A.
55.6
N.A.
44.6
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
100
100
93.3
60
N.A.
6.6
6.6
N.A.
N.A.
0
N.A.
13.3
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
100
100
93.3
73.3
N.A.
26.6
20
N.A.
N.A.
13.3
N.A.
33.3
N.A.
N.A.
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
25
0
38
0
0
0
0
0
0
0
0
13
0
% A
% Cys:
0
0
0
13
0
0
13
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
0
0
0
13
0
0
0
0
25
% D
% Glu:
0
0
0
50
13
50
0
0
63
0
50
0
50
0
13
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
38
0
25
0
0
0
0
13
0
0
0
25
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
0
38
0
25
0
0
0
0
0
0
% I
% Lys:
0
0
13
0
0
50
0
13
0
13
38
0
13
0
13
% K
% Leu:
13
0
0
13
0
0
0
0
0
0
0
0
0
0
13
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
38
% M
% Asn:
0
13
0
0
0
0
0
0
0
13
0
0
13
0
0
% N
% Pro:
25
0
0
0
0
0
0
0
0
0
0
0
0
63
0
% P
% Gln:
0
0
13
0
0
0
0
0
0
0
0
0
0
0
0
% Q
% Arg:
0
38
0
0
0
0
13
25
0
0
0
0
13
0
0
% R
% Ser:
13
50
0
25
0
0
0
0
13
0
0
0
0
0
0
% S
% Thr:
13
0
25
0
38
0
25
50
0
13
13
0
0
0
0
% T
% Val:
0
0
0
0
13
0
13
0
0
50
0
75
13
25
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _